Objective: The purpose of the study was to find out the effect of 6 weeks of Pranayama on forced expiratory volume of person with COPD. Methods: For the purpose of this study 30 male from Varanasi those who are suffering from COPD (chronic bronchitis) and under treatment process of same at S.S. hospital, IMS, B.H.U was selected purposively as the subject of the study. The age of subjects was ranged between 40 to 50 years. For the study pre-test – post-test randomized group design was used and involving 30 subjects who were grouped purposively into two groups (15 each). The first group 15 subjects were considered as control group and second 15 subjects were considered as experimental group. Forced expiratory volume was measured by pulmonary function test or Total lungs function test and scores was recorded in liters. Statistical technique: The data which was obtained from subject was analyzed statistically by the application of analysis of covariance (ANCOVA). The obtained “F” ratio was tested at .05 level of significance. Results & Conclusion: The results of the study showed that there is significant effect of 6 weeks of Pranayama on Forced expiratory volume. It is concluded that Pranayama have better effect for improvement of COPD patients in relation to Forced expiratory volume.