Systematic Approach to Training (SAT) is standard methodology for achieving training objectives. There is accumulated expertise in using SAT applications in training and in these context in fields of radiological sources safety and nuclear security. There is a need to benefit from such effective methods in Radiological safety and nuclear security education. This study review lessons learned from SAT in training and process of benefiting from these training methods into radiological sources safety and nuclear security. So, we reviewed articles and publications with key words of Systematic approach to training and radiological sources safety and nuclear security training. The basic findings is that its mandatory to have the belief of there is always an existing threat to radiological sources and that all members of the institution have to share in developing the training plans and educational needs which can be covered using systematic approach to training methods. The overall conclusion is that systematic approach to training methods is effective in raising awareness and developing the retained knowledge about safety and security of radiological sources.