Present work is dealt with the application of Mahalanobis Distance to measure the difference in dependent variables Self-efficacy, Depression, Anxiety and Stress for two groups of postgraduate students. Difference between group of students for all the dependent variables taken together at a time is not considered. Mahalanobis Distance is a powerful measure to find out the dynamical nature of group of variables. Three different dichotomous groups of students are considered for this study. Mahalanobis Distance is applied to compare the dynamical nature of five dependent variables (general self-efficacy, specific self-efficacy, depression, anxiety and stress) considered as a branch. It is found that there is no significant difference in dynamical nature of five dependent variables for different groups of independent variables.